靶向細胞因子或其受體的中和抗體是研究免疫調(diào)節(jié)和開發(fā)治療策略的有力工具。InvivoGen提供多種高品質(zhì)重組單克隆抗體(monoclonal antibody, mAb)，這些抗體源自引證詳實的生物仿制藥或自主研發(fā)的克隆產(chǎn)品。我們提供來源于人類或小鼠的細胞因子靶向和細胞因子受體靶向mAb。為保證最-佳性能，每個批次均使用對應的報告細胞和重組細胞因子進行功能測試和驗證。

主要特點

• 重組單克隆抗體

• 源自引證詳實的生物仿制藥或自主研發(fā)的

• 產(chǎn)自CHO細胞

• 經(jīng)過驗證的中和作用

• 驗證無內(nèi)毒素

• 提供InvivoFit^TM級別，可用于小鼠體內(nèi)研究

如需購買Invivogen公司產(chǎn)品，請聯(lián)系Invivogen授權代理商欣博盛生物

應 用

• 中和試驗

• 檢測和生物活性試驗

• 篩選試驗

	InvivoGen中和抗體有哪些形式？
生物仿制藥mAb 重組mAb，其特征是候選藥物或治療藥物的可變區(qū)和恒定區(qū)。 修飾同型的生物仿制藥mAb 對原始同型進行了修飾的重組生物仿制藥mAb。		自主研發(fā)的mAb 產(chǎn)自InvivoGen特-有的雜交瘤的重組mAb。在沒有可用的生物仿制藥的情況下開發(fā)。 InvivoFitTM mAbs 具有鼠源可變區(qū)和恒定區(qū)的高質(zhì)量重組mAb，專門針對小鼠體內(nèi)研究。

產(chǎn)品	靶點物種	克隆	同型	貨號
細胞因子抗體
Anti-hAPRIL-hIgG2	Human	Sibeprenlimab biosimilar - CAS # 2382896-07-1	Human IgG2	hapril-mab2
Anti-hBAFF-hIgG1	Human	Belimumab biosimilar - CAS # 356547-88-1	Human IgG1	hbaff-mab1
Anti-hCD40L-hIgG1	Human	Frexalimab biosimilar - CAS #2515463-86-0	Human IgG1	h40l-mab1
Anti-hIFN-α-hIgG1	Human	Rontalizumab biosimilar - CAS #948570-30-7	Human IgG1	hifna-mab1
Anti-hIFN-β-IgG	Human	Clone 10B10	Mouse IgG2a	mabg2-hifnb-3
Anti-hIFN-γ-hIgG1	Human	Fontolizumab biosimilar - CAS #326859-36-3	Human IgG1	hifng-mab1
Anti-hIL-1α-IgG1	Human	Clone 7D4	Human IgG1	mabg-hil1a-3
Anti-mIL-1α-mIgG1	Mouse	Clone 6H7	Mouse IgG1	mil1a-mab9-02
Anti-hIL-1β-IgG1	Human	Clone 4H5	Mouse IgG1	mabg-hil1b-3
Anti-mIL-1β-mIgG1	Mouse	Clone 7E3	Mouse IgG1	mil1b-mab9-02
Anti-mIL-2-mIgG1e3	Mouse	Clone S4B6	Mouse IgG1e3 (D265A)	mil2-mab15-02
Anti-hIL-6-IgG	Human	Clone 3H3	Mouse IgG1	mabg-hil6-3
Anti-mIL-6-mIgG1e3	Mouse	Clone 10F9	Mouse IgG1e3 (D265A)	mil6-mab15-02
Anti-hIL-9-hIgG1	Human	Enokizumab biosimilar - CAS #909875-08-7	Human IgG1	hil9-mab1
Anti-hIL-10-hIgG1	Human	Clone 20G2	Human IgG1	mab1-hil10
Anti-hIL-12/IL-23-p40-hIgG1	Human	Ustekinumab biosimilar - CAS #815610-63-0	Human IgG1	hil12p40-mab1
Anti-mIL-13-mIgG1	Mouse	Clone 8H8	Mouse IgG1	mil13-mab9-02
Anti-hIL-15-hIgG1	Human	Ordesekimab biosimilar - CAS #879293-15-9	Human IgG1	hil15-mab1
Anti-hIL-16-hIgG1	Human	Clone 14.1	Human IgG1	hil16-mab1-02
Anti-mIL-16-mIgG1e3	Mouse	Clone 14.1	Mouse IgG1e3 (D265A)	mil16-mab15-02
Anti-hIL17A-hIgG1	Human	Secukinumab biosimilar - CAS #1229022-83-6	Human IgG1	hil17a-mab1
Anti-hIL-18-hIgG1-FES	Human	Camoteskimab biosimilar - CAS #2492472-82-7	Human IgG1 (L242F/L243E/P339S)	hil18-mab16
Anti-hIL-20-hIgG4 (S228P)	Human	Fletikumab biosimilar - CAS #1357158-22-5	Human IgG4 (S228P)	hil20-mab14
Anti-hIL-21-hIgG1	Human	Avizakimab biosimilar - CAS #2229685-51-0	Human IgG1 (M252Y/S254T/T256E)	hil21-mab1
Anti-hIL-22-hIgG1	Human	Fezakinumab biosimilar - CAS #1007106-86-6	Human IgG1	hil22-mab1
Anti-hIL-25-hIgG1	Human	Clone 15G10	Human IgG1	hil25-mab1
Anti-hIL-28a-IgG	Human	Clone 21C3	Mouse IgG1	mabg-hil28a-3
Anti-hIL-28b-IgG	Human	Clone 18F4	Mouse IgG1	mabg-hil28b-3
Anti-mIL-28b-mIgG1	Mouse	Clone 3C11	Mouse IgG1	mil28b-mab9-02
Anti-hIL-29-mIgG1	Human	Clone 6A11	Mouse IgG1	mab9-hil29
Anti-hRANKL-hIgG2	Human	Denosumab biosimilar - CAS #615258-40-7	Human IgG2 (*)	hrankl-mab2
Anti-hTGF-β-hIgG4 (S228P)	Human	Fresolimumab biosimilar - CAS #948564-73-6	Human IgG4 (S228P)	htgfb-mab14
Anti-hTL1A-hIgG1	Human	Tulisokibart biosimilar - CAS #2648504-55-4	Human IgG1	htl1a-mab1
Anti-hTNF-α-hIgG1	Human	Adalimumab biosimilar - CAS #331731-18-1	Human IgG1 (*)	htnfa-mab1
Anti-hTSLP-hIgG2	Human	Tezepelumab biosimilar - CAS #1572943-04-4	Human IgG2	htslp-mab2
細胞因子受體抗體
Anti-hEGFR-hIgG1	Human	Cetuximab biosimilar - CAS #205923-56-4	Human IgG1	hegfr-mab1
Anti-hGM-CSFR-hIgG4 (S228P)	Human	Mavrilimumab biosimilar - CAS #1085337-57-0	Human IgG4 (S228P)	hgmcsfr-mab14
Anti-hIFNAR-hIgG1-FES	Human	Anifrolumab biosimilar - CAS #1326232-46-5	Human IgG1 (L242F/L243E/P339S) (*)	hifnar-mab16
Anti-hIL1RAP-hIgG1	Human	Nidanilimab biosimilar - CAS #2171061-85-9	Human IgG1	hil1rap-mab1
Anti-hIL-3R-hIgG1-DE	Human	Talacotuzumab biosimilar - CAS #1826831-79-1	Human IgG1 (S239D/I332E)	hil3r-mab18
Anti-hIL-5R-hIgG1fut	Human	Benralizumab biosimilar - CAS #1044511-01-4	Human IgG1	hil5r-mab13
Anti-hIL6R-To-hIgG1	Human	Tocilizumab biosimilar - CAS #375823-41-9	Human IgG1(*)	hil6rto-mab1
Anti-hIL-31R-hIgG2	Human	Nemolizumab biosimilar - CAS #1476039-58-3	Human IgG2	hil31r-mab2
Anti-hIL-33R-hIgG2	Human	Astegolimab biosimilar - CAS #2173054-79-8	Human IgG2	hil33r-mab2
Anti-hIL-36R-hIgG4 (S228P)	Human	Imsidolimab biosimilar - CAS #2102543-86-0	Human IgG4 (S228P)	hil36r-mab14

INVIVOFIT^TM GRADE

InvivoFit™是專為體內(nèi)研究設計的高質(zhì)量標準。InvivoFit™產(chǎn)品經(jīng)0.2μm過濾除菌，并在嚴格的無菌條件下罐裝。各批次產(chǎn)品的細菌污染物(內(nèi)毒素和脂蛋白)水平均通過瘊試劑盒(LAL)檢測以及TLR2和TLR4報告細胞檢測進行驗證。

(*) 多種同型可供選擇，詳情請聯(lián)系我們的代理商欣博盛生物，或訪問我們的網(wǎng)站。

更多詳情請聯(lián)系 InvivoGen 中國授權代理-欣博盛生物